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Ongoing Clinical Trials

Amyotrophic Lateral Sclerosis (ALS) and Depression
Researchers at USC School of Medicine are conducting an 8-week study evaluating the effectiveness of escitalopram (Lexapro®) in the treatment of Major Depression in ALS. Escitalopram is a FDA approved medication for Major Depressive Disorder.
Read more here...

Schizophrenia/Schizoaffective Disorder with Inadequate Response toTtreatment
Researchers are conducting a 6-month study of long-acting risperidone (Consta) to see if using higher doses will provide relief of symptoms that have not gone away with usual doses of antipsychotics.
Read more here...

Schizophrenia/Schizoaffective Disorder and Marijuana Use
Researchers are conducting a 3-month study to study the impact of clozapine on marijuana use to determine if medication can help people with schizophrenia reduce marijuana use and improve their mental health.
Read more here...

Schizophrenia/Schizoaffective Disorder and Alcohol Use
Researchers are conducting a 6-month study comparing two types of risperidone (Risperdal®) to determine if medication can help people with schizophrenia reduce drinking.
Read more here...

Studies Closed for Accrual:

Autism
Autism is one of the fastest growing developmental disorders that typically appears during the first three years of life and affects a person’s ability to communicate and interact with others. Autism is a spectrum disorder affecting communication and interpersonal skills to varying degrees. Autism affects nearly 1 in every 150 children, has no known cause and is a life-long disorder. Very few medications are approved to help manage some of the more severe problems children with autism often experience.
Read more here ...

Bipolar Disorder
Researchers are conducting a study to evaluate the effectiveness of aripiprazole (Abilify®) when used in combination with either lithium or valproate for the treatment of mania in Bipolar I Disorder.  It is possible for participation to last up to 58 weeks, including a 4-week Screening/Washout Period, a 2-week Lithium/Valproate Evaluation Period, a 6-Week Double-Blind Treatment Period and a 46-Week Open-Label Treatment Period.
Read more here...

Depression
Researchers are conducting a 14-week study of aripiprazole (Abilify®) to evaluate its safety and effectiveness as an add-on treatment for depression.
Read more here...

Depression
Researchers are conducting a 16-week study of antidepressants and corticotropin releasing factor (CRF), a chemical which occurs naturally in the body. Researchers will study what role CRF plays in treating symptoms of depression.
Read more here...

Schizophrenia/Schizoaffective Disorder and Weight Gain
Some people gain weight while taking medications called antipsychotics which treat the symptoms of schizophrenia. Weight gain can lead to obesity which places a person at higher risk for diabetes and heart disease. Researchers want to better understand the issues behind medications for schizophrenia and weight gain.
Read more here...

 

SHOULD YOU PARTICIPATE?

People participate in clinical research for a variety of reasons. People who volunteer for phase II and phase III trials can gain access to promising drugs long before these compounds are approved for the marketplace. They typically will get excellent care from the physicians during the course of the study. This care also may be free.
Read more here...

HOW TO SIGN UP

If you wish to participate in one of the clinical trials, select the appropriate trial from those listed to the left and contact the research team member listed in the Information link at the bottom of the trial description.

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